Une mise à jour sur les marqueurs génétiques

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Une mise à jour sur les marqueurs génétiques immunohistochimiques et moléculaires de certaines tumeurs des tissus mous

 

Current years have introduced an immense improve of data concerning the molecular genetic background of mesenchymal tumors which in flip has considerably expanded the repertoire of molecular markers obtainable for the routine diagnostic apply. This progress has additionally been adopted by a rising variety of obtainable immunohistochemical markers helpful for the analysis of soppy tissue neoplasia. Each lineage particular and tumor-specific immunohistochemical antibodies have been found and subsequently examined within the surgical pathology apply.

This text will evaluate among the immunohistochemical and molecular genetic markers helpful within the analysis of vascular tumors, malignant peripheral nerve sheath tumors, low-grade fibromyxoid sarcomas/sclerosing epithelioid fibrosarcomas, solitary fibrous tumors, epithelioid sarcomas, rhabdomyosarcomas and different lesions displaying skeletal muscle differentiation. The immunohistochemical and molecular genetic options of some not too long ago characterised and clinically significantly necessary entities will likely be mentioned as properly.

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ELISA kit for Mouse Oxidizided glutathione (GSSG)

KTE71570-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Mouse Oxidizided glutathione (GSSG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Oxidizided glutathione (GSSG)

KTE71570-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Mouse Oxidizided glutathione (GSSG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Oxidizided glutathione (GSSG)

KTE71570-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Mouse Oxidizided glutathione (GSSG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Oxidized Glutathione, 3ML

C024-3ML 3ML
EUR 254

Urea, suitable for molecular biology

GE1210-1KG 1 kg
EUR 106.8

Urea, suitable for molecular biology

GE1210-500G 500 g
EUR 76.8

Urea, suitable for molecular biology

GE1210-1 1
EUR 58

Urea, suitable for molecular biology

GE1210-500 500
EUR 33.1

Rat Oxidizided glutathione(GSSG)ELISA Kit

YLA0236RA-48T 48T
EUR 465

Rat Oxidizided glutathione(GSSG)ELISA Kit

YLA0236RA-96T 96T
EUR 600

Human Oxidizided Glutathione (GSSG) ELISA Kit

abx350842-96tests 96 tests
EUR 943.2

Mouse oxidizided glutathione(GSSG)ELISA Kit  

GA-E0190MS-48T 48T
EUR 403.2

Mouse oxidizided glutathione(GSSG)ELISA Kit  

GA-E0190MS-96T 96T
EUR 640.8

Mouse oxidizided glutathione,GSSG ELISA Kit  

YLA0510MO-48T 48T
EUR 465

Mouse oxidizided glutathione,GSSG ELISA Kit  

YLA0510MO-96T 96T
EUR 600

Human oxidizided glutathione,GSSG ELISA Kit  

YLA4329HU-48T 48T
EUR 435

Human oxidizided glutathione,GSSG ELISA Kit  

YLA4329HU-96T 96T
EUR 562.5

Oxidized Glutathione Control, 350UL

C020-350UL 350UL
EUR 85

Bovine oxidizided glutathione,GSSG ELISA Kit  

YLA0356BO-48T 48T
EUR 502.5

Bovine oxidizided glutathione,GSSG ELISA Kit  

YLA0356BO-96T 96T
EUR 618.75

Oxidized Glutathione Standard, 300UL

C020-300UL 300UL
EUR 85

Dog Oxidized Glutathione ELISA kit

E08O0028-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Oxidized Glutathione ELISA kit

E08O0028-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Oxidized Glutathione ELISA kit

E08O0028-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Oxidized Glutathione ELISA kit

E02O0341-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Oxidized Glutathione ELISA kit

E02O0341-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Oxidized Glutathione ELISA kit

E02O0341-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Oxidized Glutathione ELISA kit

E07O0341-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Oxidized Glutathione ELISA kit

E07O0341-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Oxidized Glutathione ELISA kit

E07O0341-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Oxidized Glutathione ELISA kit

E06O0341-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Oxidized Glutathione ELISA kit

E06O0341-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Oxidized Glutathione ELISA kit

E06O0341-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Oxidized Glutathione ELISA kit

E03O0341-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Oxidized Glutathione ELISA kit

E03O0341-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Oxidized Glutathione ELISA kit

E03O0341-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Oxidized Glutathione ELISA kit

E01O0028-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Oxidized Glutathione ELISA kit

E01O0028-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Oxidized Glutathione ELISA kit

E01O0028-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Oxidized Glutathione ELISA kit

E04O0341-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Oxidized Glutathione ELISA kit

E04O0341-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Oxidized Glutathione ELISA kit

E04O0341-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Oxidized Glutathione ELISA kit

E09O0341-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Oxidized Glutathione ELISA kit

E09O0341-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Oxidized Glutathione ELISA kit

E09O0341-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

GSSH ELISA Kit| General oxidized glutathione ELISA Kit

EF019615 96 Tests
EUR 826.8

Sodium chloride, suitable for molecular biology

GE0307-1 1
EUR 45.2

Sucrose, GlenBiol, suitable for molecular biology

GC3201-1KG 1 kg
EUR 90

DTT (Molecular Biology Grade)

CE131 5 g
EUR 93.6

DTT (Molecular Biology Grade)

CE132 10 g
EUR 133.2

DTT (Molecular Biology Grade)

CE133 25 g
EUR 243.6

NAD (Molecular Biology Grade)

CE196 1 g
EUR 72

NAD (Molecular Biology Grade)

CE197 5 g
EUR 165.6

NBT (Molecular Biology Grade)

CE209 1 g
EUR 123.6

NBT (Molecular Biology Grade)

CE210 5 g
EUR 360

Guinea pig Oxidized Glutathione ELISA kit

E05O0341-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Oxidized Glutathione ELISA kit

E05O0341-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Oxidized Glutathione ELISA kit

E05O0341-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig Oxidized Glutathione in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

BCIP (Molecular Biology Grade)

CE108 250 mg
EUR 75.6

BCIP (Molecular Biology Grade)

CE109 1 g
EUR 108

DAPI (Molecular Biology Grade)

CE117 5 mg
EUR 72

DAPI (Molecular Biology Grade)

CE118 25 mg
EUR 159.6

DAPI (Molecular Biology Grade)

CE119 100 mg
EUR 382.8

Tris (Molecular Biology Grade)

CE237 500 g
EUR 106.8

Tris (Molecular Biology Grade)

CE238 1 kg
EUR 153.6

Tris (Molecular Biology Grade)

CE239 5 kg
EUR 535.2

100mL Molecular Biology Grade

46-000-CI PK6
EUR 74.4

500mL Molecular Biology Grade

46-000-CV PK6
EUR 138

CHAPS (Molecular Biology Grade)

CE114 1 g
EUR 66

CHAPS (Molecular Biology Grade)

CE115 5 g
EUR 157.2

CHAPS (Molecular Biology Grade)

CE116 25 g
EUR 492

HEPES (Molecular Biology Grade)

CE171 100 g
EUR 98.4

HEPES (Molecular Biology Grade)

CE172 500 g
EUR 268.8

HEPES (Molecular Biology Grade)

CE173 1 kg
EUR 424.8

Water (Molecular Biology Grade)

CE243 500 ml
EUR 62.4

Water (Molecular Biology Grade)

CE244 1 l
EUR 67.2

Pyridine, GlenBiol™, suitable for molecular biology with molecular sieve

GS8780-2500 2500
EUR 249.8

Glycine (Molecular Biology Grade)

CE158 1 kg
EUR 84

Glycine (Molecular Biology Grade)

CE159 5 kg
EUR 228

Tween20 (Molecular Biology Grade)

CE242 1 l
EUR 106.8

Sucrose, GlenBiol™, suitable for molecular biology

GC3201-1 1
EUR 45.1

Lysozyme (Molecular Biology Grade)

CE188 1 g
EUR 70.8

Lysozyme (Molecular Biology Grade)

CE189 10 g
EUR 247.2

Pyridine, GlenBiol™, suitable for molecular biology

GS6659-2500 2500
EUR 240.3

Pyridine, GlenBiol™, suitable for molecular biology

GS6659-500 500
EUR 95.8

Formamide, GlenBiol™, suitable for molecular biology

GS9663-100 100
EUR 48.9

1L Molecular Biology Grade Water

46-000-CM PK6
EUR 196.8

Tween 20, Molecular Biology Grade

T9100-010 100ml
EUR 86.4

Tween 20, Molecular Biology Grade

T9100-050 500ml
EUR 133.2

Tween 20, Molecular Biology Grade

T9100-100 1L
EUR 160.8

D(+)-Sucrose (Molecular Biology Grade)

CE224 500 g
EUR 67.2

D(+)-Sucrose (Molecular Biology Grade)

CE225 1 kg
EUR 84

D(+)-Sucrose (Molecular Biology Grade)

CE226 5 kg
EUR 207.6

Dimethylformamide, GlenBiol™, suitable for molecular biology with molecular sieve

GS3406-2500 2500
EUR 116.2

Glycerol 87 % (Molecular Biology Grade)

CE154 1 l
EUR 93.6

MOPS buffer (Molecular Biology Grade)

CE194 100 g
EUR 102

MOPS buffer (Molecular Biology Grade)

CE195 250 g
EUR 169.2

Agarose, low EEO, GlenBiol, suitable for molecular biology

GE6258-100G 100 g
EUR 217.2

Formamide deionized (Molecular Biology Grade)

CE145 500 ml
EUR 87.6

Formamide deionized (Molecular Biology Grade)

CE146 1 l
EUR 120

D(+)-Glucose waterfree (Molecular Biology Grade)

CE148 500 g
EUR 67.2

D(+)-Glucose waterfree (Molecular Biology Grade)

CE149 1 kg
EUR 75.6

D(+)-Glucose waterfree (Molecular Biology Grade)

CE150 5 kg
EUR 180

TritonX-100 (Molecular Biology Grade)

CE240 500 ml
EUR 67.2

TritonX-100 (Molecular Biology Grade)

CE241 1 l
EUR 79.2

Dimethylsulfoxide (Molecular Biology Grade)

CE120 100 ml
EUR 66

Dimethylsulfoxide (Molecular Biology Grade)

CE121 500 ml
EUR 110.4

Dimethylformamide, GlenBiol™, suitable for molecular biology

GS6580-2500 2500
EUR 107.3

Water, distilled, GlenBiol™, suitable for molecular biology

GK8512-1L 1 l
EUR 92.4

Water, distilled, GlenBiol™, suitable for molecular biology

GK8512-1 1
EUR 60.1

Acetonitrile 50, GlenBiol™, suitable for molecular biology

GS0247-1 1
EUR 40.7

Acetonitrile 50, GlenBiol™, suitable for molecular biology

GS0247-2500 2500
EUR 61.3

Acetonitrile 10, GlenBiol™, suitable for molecular biology

GS0969-1 1
EUR 47

Acetonitrile 10, GlenBiol™, suitable for molecular biology

GS0969-2500 2500
EUR 73.9

Acetonitrile 30, GlenBiol™, suitable for molecular biology

GS8649-1 1
EUR 43.1

Acetonitrile 30, GlenBiol™, suitable for molecular biology

GS8649-2500 2500
EUR 66.5

Water, Ultrapure Molecular Biology Grade

41024-4L 4L
EUR 145.2
Description: Minimum order quantity: 1 unit of 4L

Bis-Acrylamid (Molecular Biology Grade)

CE110 50 g
EUR 94.8

Bis-Acrylamid (Molecular Biology Grade)

CE111 250 g
EUR 259.2

Sodium chloride (Molecular Biology Grade)

CE205 500 g
EUR 62.4

Sodium chloride (Molecular Biology Grade)

CE206 1 kg
EUR 70.8

Sodium chloride (Molecular Biology Grade)

CE207 5 kg
EUR 123.6

Phenol, (Carbolic acid) Double distilled for Molecular Biology

PD0252 500g
EUR 192.59

Ammonia solution, GlenBiol™, suitable for molecular biology

GS8853-100 100
EUR 91.2

Ammonium sulfate (Molecular Biology Grade)

CE105 250 g
EUR 55.2

Ammonium sulfate (Molecular Biology Grade)

CE106 1 kg
EUR 72

Ammonium sulfate (Molecular Biology Grade)

CE107 5 kg
EUR 153.6

Urea Crystalline (Molecular Biology Grade)

CE167 1 kg
EUR 72

Urea Crystalline (Molecular Biology Grade)

CE168 5 kg
EUR 181.2

Agarose, low EEO, GlenBiol™, suitable for molecular biology

GE6258-100 100
EUR 150.4

Agarose, low EEO, GlenBiol™, suitable for molecular biology

GE6258-25 25
EUR 60.1

SSC Buffer (20X) (Molecular Biology Grade)

CE229 1 l
EUR 86.4

XTT sodium salt (Molecular Biology Grade)

CE250 100 mg
EUR 208.8

XTT sodium salt (Molecular Biology Grade)

CE251 500 mg
EUR 612

Glycerol waterfree (Molecular Biology Grade)

CE155 500 ml
EUR 78

Glycerol waterfree (Molecular Biology Grade)

CE156 1 l
EUR 102

Glycerol waterfree (Molecular Biology Grade)

CE157 2.5 l
EUR 170.4

Tris - Hydrochloride (Molecular Biology Grade)

CE234 250 g
EUR 99.6

Tris - Hydrochloride (Molecular Biology Grade)

CE235 500 g
EUR 144

Tris - Hydrochloride (Molecular Biology Grade)

CE236 1 kg
EUR 223.2

NADP - sodium salt (Molecular Biology Grade)

CE200 250 mg
EUR 92.4

NADP - sodium salt (Molecular Biology Grade)

CE201 1 g
EUR 190.8

Guanidine Thiocyanate (Molecular Biology Grade)

CE164 100 g
EUR 86.4

Guanidine Thiocyanate (Molecular Biology Grade)

CE165 500 g
EUR 192

Guanidine Thiocyanate (Molecular Biology Grade)

CE166 1 kg
EUR 307.2

NADH - Disodium salt (Molecular Biology Grade)

CE198 1 g
EUR 91.2

NADH - Disodium salt (Molecular Biology Grade)

CE199 5 g
EUR 244.8

Guanidine - Hydrochloride (Molecular Biology Grade)

CE160 100 g
EUR 93.6

Guanidine - Hydrochloride (Molecular Biology Grade)

CE161 250 g
EUR 153.6

Guanidine - Hydrochloride (Molecular Biology Grade)

CE162 500 g
EUR 232.8

Guanidine - Hydrochloride (Molecular Biology Grade)

CE163 1 kg
EUR 352.8

Yeast extract powder (Molecular Biology Grade)

CE169 500 g
EUR 133.2

Hyaluronidase Grade I (Molecular Biology Grade)

CE174 1 g
EUR 232.8

Hyaluronidase Grade I (Molecular Biology Grade)

CE175 5 g
EUR 920.4

NADPH - Tetrasodium salt (Molecular Biology Grade)

CE202 25 mg
EUR 70.8

NADPH - Tetrasodium salt (Molecular Biology Grade)

CE203 100 mg
EUR 126

NADPH - Tetrasodium salt (Molecular Biology Grade)

CE204 500 mg
EUR 374.4

3-Methylbutan-1-ol, GlenBiol™, suitable for molecular biology

GS6015-100 100
EUR 74.5

3-Methylbutan-1-ol, GlenBiol™, suitable for molecular biology

GS6015-500 500
EUR 301.4

TRIS-Glycine Buffer 10X, GlenBiol™, suitable for molecular biology

GE6710-1 1
EUR 67.9

Les changements transcriptionnels dans la rhinosinusite chronique avec asthme favorisent un endotype moléculaire de kind 2 indépendant du statut polype 

Background: Information concerning the inflammatory profile of sufferers with bronchial asthma and persistent rhinosinusitis (CRS-A) with (CRSwNP-A) and with out (CRSsNP-A) nasal polyposis stay restricted.

Goal: Outline and evaluate systemic transcriptional modifications in sufferers with CRS-A to these with non-asthma-related CRS with (CRSwNP) and with out nasal polyposis (CRSsNP).

Strategies: Thirty-four sufferers with CRS-A (n=19) and CRS (n=15) had been prospectively enrolled into an observational examine. Demographic data and subjective and goal illness severity measures had been recorded. Multiplex gene expression evaluation of mRNA extracted from peripheral blood was carried out. A complete of 594 genes related to innate/adaptive immunity had been analyzed utilizing NanoString expertise. Gene expression ratios had been reported for genes that had been differentially expressed amongst these cohorts. Linear regression evaluation was used to evaluate the mRNA transcript copy numbers for every gene with illness severity.

Outcomes: There was no vital distinction in age, gender, nasal polyposis, or health-related high quality of life measures between the 2 teams (p>0.05). HLA class II histocompatibility antigen, DRB3-1 beta chain (HLA-DRB3) was considerably upregulated within the peripheral blood of sufferers with CRSsNP-A in comparison with CRSsNP, whereas chemokine (C-C motif) ligands 4 (CCL4) and zinc finger protein helios (IKZF2) had been considerably upregulated in CRSwNP-A in comparison with CRSwNP (p<0.05).

Conclusion: Sufferers with CRSsNP-A display a molecular endotype related to a Th2-dominant inflammatory profile in comparison with CRSsNP. Sufferers with CRSwNP-A equally display an overrepresentation of genes related to Th2-driven irritation in comparison with sufferers with CRSwNP.

Caractérisation moléculaire de la blastocystie chez les primates du Nouveau Monde en captivité et en liberté, Platyrrhini 

Objective: Blastocystis species are extensively distributed micro-eukaryote parasites present in each human and nonhuman primates. Regardless of having a worldwide distribution, descriptions of Blastocystis subtype range in neotropical primates is largely restricted to captive animals. The purpose of this examine was to molecularly characterize the presence of Blastocystis in free-ranging black-headed evening monkeys, Aotus nigriceps, and to investigate Blastocystis heterogeneity in primates of the Parvorder Platyrrhini.

Strategies: We analyzed Blastocystis small sub-unit ribosomal DNA (SSUrDNA) from each A. nigriceps and Azara’s evening monkey, A. azarae boliviensis, in Southeastern Peru. We additionally included extra Blastocystis sequence from different neotropical primate research to discover the distribution and host specificity of Blastocystis subtypes (ST) all through the neotropics.

Outcomes: 13 p.c of A. nigriceps samples had been Blastocystis optimistic. Solely ST8 was amplified in A. nigriceps and this partial DNA sequence was extremely just like ST8 sequence beforehand obtained from a human in Brazil. In our evaluation of all obtainable Blastocystis SSU sequences from primates of the Parvorder Platyrrhini, we discovered 15 monophyletic lineages comparable to beforehand described subtypes ST1-ST10, ST12-15, and ST17.

Conclusions: Blastocystis SSU sequences amplified from A. nigriceps fecal samples shared excessive sequence similarity to isolates discovered in a number of different neotropical primates, Alouatta palliata, A. caraya, Ateles fusciceps, and Lagothrix. Related subtypes have been present in human and captive primates which helps the opportunity of transmission when in shut contact. Expanded sampling of sympatric neotropical primates within the wild will set up whether or not subtypes and clades are restricted to taxonomic group or whether or not transmission happens between overlapping species.

Commencement du gliome, classification des caractéristiques moléculaires et caractérisation microstructurale à l’aide de l’imagerie par décomposition de la variance par diffusion (DIVIDE) RM 

Goal: To judge the potential of diffusional variance decomposition (DIVIDE) for grading, molecular function classification, and microstructural characterization of gliomas.

Supplies and strategies: Members with suspected gliomas underwent DIVIDE imaging, yielding parameter maps of fractional anisotropy (FA), imply diffusivity (MD), anisotropic imply kurtosis (MKA), isotropic imply kurtosis (MKI), complete imply kurtosis (MKT), MKA/MKT, and microscopic fractional anisotropy (μFA). Tumor kind and grade, isocitrate dehydrogenase (IDH) half mutant standing, and the Ki-67 labeling index (Ki-67 LI) had been decided after surgical procedure. Statistical evaluation included 33 high-grade gliomas (HGG) and 17 low-grade gliomas (LGG). Tumor diffusion metrics had been in contrast between HGG and LGG, amongst grades, and between wild and mutated IDH varieties utilizing applicable checks in keeping with normality evaluation outcomes. Receiver working attribute and Spearman correlation evaluation had been additionally used for statistical evaluations.

Outcomes: FA, MD, MKA, MKI, MKT, μFA, and MKA/MKT differed between HGG and LGG (FA: p = 0.047; MD: p = 0.037, others p < 0.001), and amongst glioma grade II, III, and IV (FA: p = 0.048; MD: p = 0.038, others p < 0.001). All diffusion metrics differed between wild-type and mutated IDH tumors (MKI: p = 0.003; others: p < 0.001). The metrics that finest discriminated between HGG and LGGs and between wild-type and mutated IDH tumors had been MKT and FA respectively (space beneath the curve 0.866 and 0.881). All diffusion metrics besides FA confirmed vital correlation with Ki-67 LI, and MKI had the best correlation coefficient (rs = 0.618).

Conclusion: DIVIDE is a promising approach for glioma characterization and analysis.

DTT (Molecular Biology Grade)

CE131 5 g
EUR 93.6

DTT (Molecular Biology Grade)

CE132 10 g
EUR 133.2

DTT (Molecular Biology Grade)

CE133 25 g
EUR 243.6

NAD (Molecular Biology Grade)

CE196 1 g
EUR 72

NAD (Molecular Biology Grade)

CE197 5 g
EUR 165.6

NBT (Molecular Biology Grade)

CE209 1 g
EUR 123.6

NBT (Molecular Biology Grade)

CE210 5 g
EUR 360

BCIP (Molecular Biology Grade)

CE108 250 mg
EUR 75.6

BCIP (Molecular Biology Grade)

CE109 1 g
EUR 108

DAPI (Molecular Biology Grade)

CE117 5 mg
EUR 72

DAPI (Molecular Biology Grade)

CE118 25 mg
EUR 159.6

DAPI (Molecular Biology Grade)

CE119 100 mg
EUR 382.8

Tris (Molecular Biology Grade)

CE237 500 g
EUR 106.8

Tris (Molecular Biology Grade)

CE238 1 kg
EUR 153.6

Tris (Molecular Biology Grade)

CE239 5 kg
EUR 535.2

100mL Molecular Biology Grade

46-000-CI PK6
EUR 74.4

500mL Molecular Biology Grade

46-000-CV PK6
EUR 138

CHAPS (Molecular Biology Grade)

CE114 1 g
EUR 66

CHAPS (Molecular Biology Grade)

CE115 5 g
EUR 157.2

CHAPS (Molecular Biology Grade)

CE116 25 g
EUR 492

HEPES (Molecular Biology Grade)

CE171 100 g
EUR 98.4

HEPES (Molecular Biology Grade)

CE172 500 g
EUR 268.8

HEPES (Molecular Biology Grade)

CE173 1 kg
EUR 424.8

Water (Molecular Biology Grade)

CE243 500 ml
EUR 62.4

Water (Molecular Biology Grade)

CE244 1 l
EUR 67.2

Pyridine, GlenBiol™, suitable for molecular biology with molecular sieve

GS8780-2500 2500
EUR 249.8

Glycine (Molecular Biology Grade)

CE158 1 kg
EUR 84

Glycine (Molecular Biology Grade)

CE159 5 kg
EUR 228

Tween20 (Molecular Biology Grade)

CE242 1 l
EUR 106.8

Lysozyme (Molecular Biology Grade)

CE188 1 g
EUR 70.8

Lysozyme (Molecular Biology Grade)

CE189 10 g
EUR 247.2

Pyridine, GlenBiol™, suitable for molecular biology

GS6659-2500 2500
EUR 240.3

Pyridine, GlenBiol™, suitable for molecular biology

GS6659-500 500
EUR 95.8

Formamide, GlenBiol™, suitable for molecular biology

GS9663-100 100
EUR 48.9

1L Molecular Biology Grade Water

46-000-CM PK6
EUR 196.8

Tween 20, Molecular Biology Grade

T9100-010 100ml
EUR 86.4

Tween 20, Molecular Biology Grade

T9100-050 500ml
EUR 133.2

Tween 20, Molecular Biology Grade

T9100-100 1L
EUR 160.8

Dimethylformamide, GlenBiol™, suitable for molecular biology with molecular sieve

GS3406-2500 2500
EUR 116.2

Glycerol 87 % (Molecular Biology Grade)

CE154 1 l
EUR 93.6

MOPS buffer (Molecular Biology Grade)

CE194 100 g
EUR 102

MOPS buffer (Molecular Biology Grade)

CE195 250 g
EUR 169.2

Agarose, low EEO, GlenBiol, suitable for molecular biology

GE6258-100G 100 g
EUR 217.2

Formamide deionized (Molecular Biology Grade)

CE145 500 ml
EUR 87.6

Formamide deionized (Molecular Biology Grade)

CE146 1 l
EUR 120

TritonX-100 (Molecular Biology Grade)

CE240 500 ml
EUR 67.2

TritonX-100 (Molecular Biology Grade)

CE241 1 l
EUR 79.2

Dimethylsulfoxide (Molecular Biology Grade)

CE120 100 ml
EUR 66

Dimethylsulfoxide (Molecular Biology Grade)

CE121 500 ml
EUR 110.4

Dimethylformamide, GlenBiol™, suitable for molecular biology

GS6580-2500 2500
EUR 107.3

Water, distilled, GlenBiol™, suitable for molecular biology

GK8512-1L 1 l
EUR 92.4

Water, distilled, GlenBiol™, suitable for molecular biology

GK8512-1 1
EUR 60.1

Acetonitrile 50, GlenBiol™, suitable for molecular biology

GS0247-1 1
EUR 40.7

Acetonitrile 50, GlenBiol™, suitable for molecular biology

GS0247-2500 2500
EUR 61.3

Acetonitrile 10, GlenBiol™, suitable for molecular biology

GS0969-1 1
EUR 47

Acetonitrile 10, GlenBiol™, suitable for molecular biology

GS0969-2500 2500
EUR 73.9

Acetonitrile 30, GlenBiol™, suitable for molecular biology

GS8649-1 1
EUR 43.1

Acetonitrile 30, GlenBiol™, suitable for molecular biology

GS8649-2500 2500
EUR 66.5

Water, Ultrapure Molecular Biology Grade

41024-4L 4L
EUR 145.2
Description: Minimum order quantity: 1 unit of 4L

Bis-Acrylamid (Molecular Biology Grade)

CE110 50 g
EUR 94.8

Bis-Acrylamid (Molecular Biology Grade)

CE111 250 g
EUR 259.2

Sodium chloride (Molecular Biology Grade)

CE205 500 g
EUR 62.4

Sodium chloride (Molecular Biology Grade)

CE206 1 kg
EUR 70.8

Sodium chloride (Molecular Biology Grade)

CE207 5 kg
EUR 123.6

Phenol, (Carbolic acid) Double distilled for Molecular Biology

PD0252 500g
EUR 192.59

Ammonia solution, GlenBiol™, suitable for molecular biology

GS8853-100 100
EUR 91.2

Ammonium sulfate (Molecular Biology Grade)

CE105 250 g
EUR 55.2

Ammonium sulfate (Molecular Biology Grade)

CE106 1 kg
EUR 72

Ammonium sulfate (Molecular Biology Grade)

CE107 5 kg
EUR 153.6

Urea Crystalline (Molecular Biology Grade)

CE167 1 kg
EUR 72

Urea Crystalline (Molecular Biology Grade)

CE168 5 kg
EUR 181.2

Agarose, low EEO, GlenBiol™, suitable for molecular biology

GE6258-100 100
EUR 150.4

Agarose, low EEO, GlenBiol™, suitable for molecular biology

GE6258-25 25
EUR 60.1

SSC Buffer (20X) (Molecular Biology Grade)

CE229 1 l
EUR 86.4

XTT sodium salt (Molecular Biology Grade)

CE250 100 mg
EUR 208.8

XTT sodium salt (Molecular Biology Grade)

CE251 500 mg
EUR 612

Glycerol waterfree (Molecular Biology Grade)

CE155 500 ml
EUR 78

Glycerol waterfree (Molecular Biology Grade)

CE156 1 l
EUR 102

Glycerol waterfree (Molecular Biology Grade)

CE157 2.5 l
EUR 170.4

Tris - Hydrochloride (Molecular Biology Grade)

CE234 250 g
EUR 99.6

Tris - Hydrochloride (Molecular Biology Grade)

CE235 500 g
EUR 144

Tris - Hydrochloride (Molecular Biology Grade)

CE236 1 kg
EUR 223.2

NADP - sodium salt (Molecular Biology Grade)

CE200 250 mg
EUR 92.4

NADP - sodium salt (Molecular Biology Grade)

CE201 1 g
EUR 190.8

Guanidine Thiocyanate (Molecular Biology Grade)

CE164 100 g
EUR 86.4

Guanidine Thiocyanate (Molecular Biology Grade)

CE165 500 g
EUR 192

Guanidine Thiocyanate (Molecular Biology Grade)

CE166 1 kg
EUR 307.2

NADH - Disodium salt (Molecular Biology Grade)

CE198 1 g
EUR 91.2

NADH - Disodium salt (Molecular Biology Grade)

CE199 5 g
EUR 244.8

Guanidine - Hydrochloride (Molecular Biology Grade)

CE160 100 g
EUR 93.6